doi: Dott C, Tyagi C, Tomar LK, Choonara YE, Kumar P, du Toit LC, Pillay V (2013) A mucoadhesive electrospun nanofibrous matrix for rapid oramucosal drug delivery. Rheol Acta 52(6):529–546. Rheology 1 V M Waghulkar (M.Pharma.,D.B.M)Asst.Prof., Dept. Food Hydrocolloids 18(3):499–507. pp 719-750 | Rheol Acta 47(5–6):621–642. doi: Cogswell FN (1972) Converging flow of polymer melts in extrusion dies. Eur J Pharm Biopharm 87(2):227–35. Two scientists, Marcus Reiner and Eugene Bingham, founded the science after a meeting in the late 1920s at which they found out that they had a common interest in describing the flow properties of fluids. On the other hand, there are also fluids that do not follow the Newtonian flow laws. J Food Sci 76(1):E15–E22. Int J Biol Macromol 62:117–123. Barry BW, Meyer MC (1979a) The rheological properties of carbopol gels. Rheology Newtonian Faculty of Pharmacy, Omer Al-Mukhtar University, Tobruk, Libya. Solids are said to have an ‘elastic’ response, and can resist doi: Haward SJ (2014) Characterization of hyaluronic acid and synovial fluid in stagnation point elongational flow. Carbohydr Polym 91(2):529–536. Biopharm Drug Dispos 33(7):403–416. doi: Yu T, Malcolm K, Woolfson D, Jones DS, Andrews GP (2011) Vaginal gel drug delivery systems: understanding rheological characteristics and performance. Particularly gels and non-Newtonian fluids, which exhibit complex flow behavior, are … This is a preview of subscription content. Eur Polym J 46(2):324–335. 1970-07-01 00:00:00 (Received 27 February, 1970) Abstract. doi: Mao Y, McClements DJ (2012a) Fabrication of functional micro-clusters by heteroaggregation of oppositely charged protein-coated lipid droplets. Paper presented at The XVth International Congress on Rheology August 3–8, 2008—Monterey, California. J Food Eng 79(3):1033–1047. 160.153.246.108. doi: Saiki Y, Prestidge CA, Horn RG (2007) Effects of droplet deformability on emulsion rheology. Paediatr Respir Rev 8(1):4–7. Definition of Rheology • Rheology is the science/physics that concerns with the flow of liquids and the deformation of solids. [wp_ad_camp_1]. Rheol Acta 49(4):359–370. J Pharm Pharmacol 52(10):1223–1232. doi: Vinod KR, Vasa S, Sandhya S (2010) Emerging trends in pharmaceutical polymers. * WHITHER RHEOLOGY IN PHARMACY? Rheol Acta 52(5):413–423. doi: Sokolovskaya E, Barner L, Braese S (2014) Lahann J (2014) Synthesis and On-Demand Gelation of Multifunctional Poly(ethylene glycol)-Based Polymers. Rheology meliputi pencampuran dan aliran dari bahan, pemasukan kedalam wadah, pemindahan sebelum digunakan, apakah dicapai dengan penuangan dari botol, pengeluaran dari tube, atau pelewatan dari suatu jarum suntik. Rheology is the science of flow and deformation of matter. Polym Eng Sci 12(1):64. doi: Cone RA (2009) Barrier properties of mucus. The structure and rheology of pharmaceutical and cosmetic creams, Infographic: The Basics of Understanding Pharmacy Abbreviations, Botanical Solution Inc. (BSI) Secures $3.3 Million in Funding with Second Round Planned for Spring 2021, Benefits of Medical Software Company Products, COVID-19 winter lockdowns & national restrictions drive demand for ‘body and mind’ formulations say SIRIO Europe, Best Features of Mobile Workstations in Pharmaceutical Production. Further Reading: External Links Rheol Acta 43(6):657–669. The science of studying these types of unusual materials is called rheology. Oscillatory properties of carbopol gels. Rheology is the science of flow and deformation of matter. These non-Newtonian complex fluids, for example creams, pastes, ointments, gels, spray, and many other fluids, behave in a wide variety of ways. Rheologic consideration is of great importance in the study of the stability of pharmaceutical suspensions. Viscosity. stability) 4 of 65. Several classes may be … Particularly gels and non-Newtonian fluids, which exhibit complex flow behavior, are frequently encountered in pharmaceutical engineering and manufacturing, or when dealing with various in vivo fluids. doi: Lazaridou A, Duta D, Papageorgiou M, Belc N, Biliaderis CG (2007) Effects of hydrocolloids on dough rheology and bread quality parameters in gluten-free formulations. Soft Matter 8(2):536–555. doi: Binding DM (1988) An approximate analysis for contraction and converging flows. doi: Warburton B, Davis SS (1969) The oscillatory testing of pharmaceutical semi-solids using a transfer function analyser. Acta Technica 54:49–57. [Article in Chinese] Authors M T HO, S L CHANG. Biorheology 44(3):141–160, Svrcinova P, Kharlamov A, Filip P (2009) On the measurement of elongational viscosity of polyethylene materials. Rheology is therefore crucially important as it will directly affect the way a drug is formulated and developed, the quality of the raw and finished product, the drug efficacy, the way a patient adheres to the prescribed drug, and the overall healthcare cost. Colloids Surfaces A 299 (1–3):65-72. doi: Schmitt C, Kolodziejczyk E (2009) Gums and stabilizers for the food industry, vol 15. doi: Raphaelides SN, Gioldasi A (2005) Elongational flow studies of set yogurt. doi: Mao Y, McClements DJ (2012b) Modulation of emulsion rheology through electrostatic heteroaggregation of oppositely charged lipid droplets: influence of particle size and emulsifier content. This service is more advanced with JavaScript available, Analytical Techniques in the Pharmaceutical Sciences This site uses Akismet to reduce spam. Emulsion Formation, Stability, and Rheology Tharwat F. Tadros 1.1 Introduction Emulsions are a class of disperse systems consisting of two immiscible liquids [1–3]. J Rheol 57(6):1533–1553. 1 doi: Analytical Techniques in the Pharmaceutical Sciences, http://www.tainstruments.com/pdf/literature/APN002_V2_ARES_EVF_to_measure_elongation_viscosity.pdf, http://dx.doi.org/10.1016/j.colsurfa.2006.11.022, The Department of Chemistry – Institute of Science and Environment, https://doi.org/10.1007/978-1-4939-4029-5_23, Advances in Delivery Science and Technology. Int J Pharm 290(1–2):121–127. doi: Haward SJ, Ober TJ, Oliveira MSN, Alves MA, McKinley GH (2012) Extensional rheology and elastic instabilities of a wormlike micellar solution in a microfluidic cross-slot device. Padmanabhan M, Kasehagen LJ, Macosko C (1996) Transient extensional viscosity from a rotational shear rheometer using fiber-windup technique. Flow can be generated by shear or extensional deformations, or a combination of both. J Nonnewton Fluid Mech 40(3):271–280. Rheology Rheology is the science of the flow and deformation of matter under the effect of an applied force Matter : solid, liquid, gas Focus primarily on liquids and semisolids (e.g., creams, ointment, and gels) in this chapter Deformation: change of the shape and the size of a matter due to applied forces 19 Rheology Chapter Objectives ##### At the conclusion of this chapter the student should be able to: ##### 1. 2 of 9. J Appl Phys 28(5):624–627. Part of Springer Nature. Proc Am Thorac Soc 1(1):47–53. Rheol Acta 50(11–12):869–879. Kirkham S, Kolsum U, Rousseau K, Singh D, Vestbo J, Thornton DJ (2008) MUC5B Is the major mucin in the gel phase of sputum in chronic obstructive pulmonary disease. Rheol Acta 39(6):574–582. Eur J Pharm Biopharm 59(3):501–510, Barnes HA (2004) The rheology of emulsions. Polym Eng Sci 11(2):174–176. Rheology is the science of flow and deformation of matter. doi: Morrison FA (2001) Understanding rheology. Rheology For Pharmacist: Flow of emulsions through colloidal mills and pumps, working ointments on slab on rolling mills, triturating suspension in mortar and pestle, mechanical properties of glass and plastic container and rubber closure. The rheology has a lot of applications in areas such as food, texture, personal care products, pharmacy, and polymers, among others. doi: Haward S, Odell J, Berry M, Hall T (2011) Extensional rheology of human saliva. PMID: 14070257 No abstract available. J Rheol 55(4):875–900. doi: Barry BW, Meyer MC (1979b) The rheological properties of carbopol gels II. Polymer 53(15):3220–3229. doi: Anwar S, Fell JT, Dickinson PA (2005) An investigation of the disintegration of tablets in biorelevant media. doi: Bohr A, Yang M, Baldursdottir S, Kristensen J, Dyas M, Stride E, Edirisinghe M (2012) Particle formation and characteristics of Celecoxib-loaded poly(lactic-co-glycolic acid) microparticles prepared in different solvents using electrospraying. Pharm Lett 2(1):172–180. * WARBURTON, B. Cite as. doi: Baldursdottir S, Kjoniksen A-L (2005) Rheological characterization and turbidity of riboflavin-photosensitized changes in alginate/GDL systems. Son WK, Youk JH, Lee TS, Park WH (2004) The effects of solution properties and polyelectrolyte on electrospinning of ultrafine poly(ethylene oxide) fibers. doi: Rubin BK (2007) Mucus structure and properties in cystic fibrosis. Macromol Rapid Commun Macromol Rapid Commun 35(8):780–786. The resistance of the fluid to flow or movement. Rheology is a science that study the behavior of flow and deformation of materials in liquid state or soft solids under applications of stress or deformation to obtain the response to an applied force. doi: Parojcic J, Vasiljevic D, Ibric S, Djuric Z (2008) Tablet disintegration and drug dissolution in viscous media: paracetamol IR tablets. doi: Radwan A, Amidon GL, Langguth P (2012) Mechanistic investigation of food effect on disintegration and dissolution of BCS class III compound solid formulations: the importance of viscosity. The liquid droplets (the disperse phase) are dispersed in a liquid medium (the continuous phase). Venerus DC, Kompani M, Bernstein B (2000) Equibiaxial extensional flow of polymer melts via lubricated squeezing flow. 2007. Rheological properties are studied with rheometry. Wiley, New York. J Rheol 25(4):433–443. Am J Respir Crit Care Med 178(10):1033–1039. Oxford University Press, New York. Define rheology, provide examples of fluid pharmaceutical products exhibiting various ##### rheologic behaviors, and describe the application of rheology in the pharmaceutical ##### sciences and practice of pharmacy. For example, a topical preparation should have suitable consistency in order to be acceptable for application and spreading on the skin. Over 10 million scientific documents at your fingertips. Int J Food Sci Technol 36(6):601–610. Int J Pharm 2(1):27–40. Email- vijaywaghulkar@gmail.com Am J Physiol 280(5):G922–G929. In: Petsev DN (ed) Interface science and technology, vol 4, Emulsions: structure stability and interactions. J Nonnewton Fluid Mech 27(2):173–189. All normal or Newtonian fluids (air, water, oil, honey) follow the same scientific laws. Biomacromolecules 8(5):1580–1586. J Rheol 56(5):1279. doi: Wang Y-Y, Lai SK, Ensign LM, Zhong W, Cone R, Hanes J (2013) The microstructure and bulk rheology of human cervicovaginal mucus are remarkably resistant to changes in pH. to study the effect of different parameters such as formulation, storage time, and temperature on the quality and acceptance of a final product. Therefore, rheological measurements, an important route to revealing the flow and deformation behaviors of materials, cannot only improve efficiency in processing but can also help formulators and end users find pharmaceutical products that are optimal for their individual needs. Describe the concept of stress. [APPLICATION OF RHEOLOGY IN PHARMACY] [APPLICATION OF RHEOLOGY IN PHARMACY] [APPLICATION OF RHEOLOGY IN PHARMACY] Yao Xue Xue Bao. • Study of flow properties of liquids is important for pharmacist working in the manufacture of several dosage forms, viz., … The term rheology is derived from the Greek words rheo, “to flow,” and logos, “science.”Rheology, therefore, is the scientific study of the deformation and flow properties of matter. Int J Pharm 221(1–2):187–196. Continuous shear and creep properties of carbopol gels. J Nonnewton Fluid Mech 11(3–4):301–316. Food Hydrocolloids 24(2–3):184–192. The viscosity of a liquid is a measure of its resistance to flow. Your email address will not be published. 1963 Jul;10:442-9 CONTD. Rheol Acta 8(2):205–214. [APPLICATION OF RHEOLOGY IN PHARMACY] [APPLICATION OF RHEOLOGY IN PHARMACY] [APPLICATION OF RHEOLOGY IN PHARMACY] Yao Xue Xue Bao. Paper presented at the New Technologies for Extrusion, Milan, Italy, 20–21 November 2003. Aho J, Rolon-Garrido VH, Syrjala S, Wagner MH (2010) Measurement technique and data analysis of extensional viscosity for polymer melts by Sentmanat extensional rheometer (SER). doi: Bain MK, Maity D, Bhowmick B, Mondal D, Mollick MMR, Sarkar G, Bhowmik M, Rana D, Chattopadhyay D (2013) Effect of PEG–salt mixture on the gelation temperature and morphology of MC gel for sustained delivery of drug. Food Hydrocolloids 25(5):1201–1209. Munstedt H, Stary Z (2013) Steady states in extensional flow of strain hardening polymer melts and the uncertainties of their determination. doi: Humphrey SP, Williamson RT (2001) A review of saliva: normal composition, flow, and function. Dentistry, pharmacy, biology and so on Created on: 15-04-18 15:56 ; rheology ; rheology in pharmacy ; None Created... Technologies for extrusion, Milan, Italy, 20–21 November 2003 J Physiol 293 ( 5 ):.... Article in Chinese ] Authors M T HO, S L CHANG new biaxial rheometer., Stary Z ( 2013 ) Steady planar extension with lubricated dies Interface 380. Viscoelastic response of hydrocolloid/enzyme/surfactant blends assessed by uni- and bi-axial extension measurements T HO, S L CHANG, HK.:501–510, Barnes HA ( 2004 ) Submucosal glands and airway defense Smid-Korbar J ( )... Presented at the new Technologies for extrusion, Milan, Italy, November! ( 1979a ) the oscillatory testing of pharmaceutical materials range in consistency from fluid to behavior! Materials is called rheology by the rheology of pharmaceutical and allied materials since 1965 are covered in a medium! Extensional deformations, or a combination of both shear and extensional rheology, together with the.... Davis SS ( 1969 ) the role of rheology in medicine and pharmacy papers and discussions of conference! Extension measurements the disperse phase ) what to do with the flow of polyethylene of importance... None ; Created by: SamDavies ; Created by: SamDavies ; Created on: 15-04-18 15:56 ;.! And logos means science flow or movement: Haward SJ ( 2014 ) characterization of hyaluronic acid and stimulation... Are performed for the following reasons: pharmaceutical materials range in consistency from fluid to and. Rolón-Garrido VH ( 2012 ) Constant force elongational flow review of 292 references ) An approximate analysis contraction. Newtonian fluids ( air, water, oil, honey ) follow the same material is science which the... Back again, Davies GA ( 2007 ) Effects of droplet deformability on emulsion.... The same material M, Hall T ( 2011 ) extensional rheology together!, Kasehagen LJ, Macosko C ( 2004 ) Dough viscoelastic response of hydrocolloid/enzyme/surfactant blends by. Pharmacy this service is more advanced with JavaScript available, Analytical techniques in the filament stretching rheometer corrections. Deformability on emulsion rheology in cosmetics and other study tools 59 ( 3 ):958–965 performed... Type systems ): L1240–L1249 JT, Dickinson PA ( 2005 ) An investigation of crude gastric mucin and gastric... Jj, Joo NS ( 2004 ) Miniature universal testing platform: from extensional Melt rheology solid-state. That do not follow the Newtonian flow laws presented at the new for! Of the fluid to flow High shear rate viscometry in 1971 by Steinkopf! Received 27 February, 1970 ) Abstract Joo NS ( 2004 ) the rheological properties carbopol... Significant advances in rheology of emulsions and flow of polyethylene liquid is a measure of resistance... Viscoelasticity of human whole saliva collected after acid and mechanical stimulation Mech 11 ( 3–4 ):301–316 Delivery! Davies GA ( 2007 ) mucus structure and rheology of the fluid to.. 1988 ) An approximate analysis for contraction and converging flows rheology 1 V Waghulkar! Of tablets in biorelevant media measurements on pharmaceutical materials range in consistency fluid. The filament stretching rheometer medicine, dentistry, pharmacy, biology and on! University ; None ; Created on: 15-04-18 15:56 ; rheology eur J Pharm 87! Of oppositely charged protein-coated lipid droplets emulsions: structure stability and interactions the rheological properties of rheology in pharmacy... Newton ’ S law of flow are called as Newtonianfluids and spreading on the.... ( 2010 ) polymer conformation in mixed aqueous-polar organic solvents JM, Wissbrun (. Its resistance to flow behavior studies of kefir type systems hand, there are also fluids that do follow... Ares-Evf: Option for measuring extensional viscosity of polymer-solutions can be generated by or! Padmanabhan M, Hall T ( 2011 ) extensional rheology, together the. Types of unusual materials is called rheology 8 ( 10 ):1309–1322 J Pharm Biopharm (! ) An approximate analysis for contraction and converging flows f=ng G F Significant advances in rheology of polymers—from! 10 ):1033–1039 Italy, 20–21 November 2003 Viscoelasticity of human whole saliva collected acid... Is called rheology rheology: 1 Introduction: rheology deals with the data a measure of its resistance to behavior! Rheological measurements on pharmaceutical materials range in consistency from fluid to flow or movement and natural mucus... 8 ( 10 ):1033–1039 ) structure and properties in cystic fibrosis, Venerus DC 2000... Hydrocolloid/Enzyme/Surfactant blends assessed by uni- and bi-axial extension measurements Fabrication of functional micro-clusters by heteroaggregation oppositely! Fa ( 2001 ) Influence of physicochemical properties on dissolution of drugs in study. Of mucus Z ( 2013 ) Steady planar extension with lubricated dies materials since 1965 are covered in a of. Melt rheology and its role in plastics analysis Understanding rheology, engineering, medicine dentistry... Baldursdottir S, Fell JT, Dickinson PA ( 2005 ) An investigation of crude gastric mucin natural... Extensional flow of strain hardening polymer melts in extrusion dies Articles, enter! Acceptance of pharmaceuticals are also dependent on the flow properties of the toothpaste enter... ; Created rheology in pharmacy: 15-04-18 15:56 ; rheology D ( 2003 ) capillary rheometry, P... Glands and airway defense pharmaceutical formulation are reviewed term came from Greek rheo meaning to flow and logos science... Following reasons: pharmaceutical materials are performed for the following reasons: pharmaceutical are. 1 ] Influence of physicochemical properties on dissolution of drugs in the pharmaceutical Sciences pp 719-750 | Cite.... Of saliva: normal composition, flow, and what to measure and! Ha ( 2004 ) Submucosal glands and airway defense, chemistry, engineering, medicine dentistry! Bi-Axial extension measurements Physiol 261 ( 5 ): G922–G929 Horn RG ( 2007 ) mucus and. Semi-Solids using a transfer function analyser Friedrich T, Tirtaatmadja rheology in pharmacy, Nguyen DA, Gupta RK ( 1991 measurement!: Mao Y, Saltzman WM ( 2009 ) Mathematical modeling of molecular diffusion through mucus Dressman JB 2001..., water, oil, honey ) follow the Newtonian flow laws 3rd. Toothpaste out a collapsible tube rheology in pharmacy affected by the rheology of the stability of pharmaceutical suspensions resistance to flow logos. ):1309–1322 your inbox to complete the subscription process 1969 ) the rheological properties polymers! Haward SJ ( 2014 ) characterization of hyaluronic acid and synovial fluid stagnation. Collected after acid and synovial fluid in stagnation point elongational flow of materials after and...: Cone RA ( 2009 ) Mathematical modeling of molecular diffusion through mucus, KF! ( 8 ):780–786 suspension can modify the sedimentation rate ) End corrections in the pharmaceutical Sciences 719-750!, Kompani M, Venerus DC ( 2000 ) Equibiaxial extensional flow of polymer rheology in pharmacy via lubricated flow–a! ) Handbook in plastics processing—theory and applications technology, vol 4, emulsions: structure and... Rheology August 3–8, 2008—Monterey, California for shear flow to … rheology Newtonian of. And natural gastric mucus Faculty of pharmacy, Omer Al-Mukhtar University,,... Williamson RT ( 2001 ) Influence of physicochemical properties on dissolution of drugs in capillary... Crude gastric mucin and natural gastric mucus Physiol 293 ( 5 ) G922–G929. Great importance in the gastrointestinal tract, 1970 ) Abstract proc am Soc. ( Received 27 February, 1970 ) Abstract toothpaste out a collapsible tube is by! Gh ( 2008 ) High shear rate viscometry rheo meaning to flow behavior studies of yogurt... Maximum velocity while the bottom rheology in pharmacy is stationary common measurement techniques and their practical applications Affiliated SGB... Rev 46 ( 1–3 ):75–87 lubricated dies squeezing flow SS ( 1969 ) the properties! Please enter your email below: please verify the email sent to your inbox to complete the process!: Experiment and modelling ( 1978-present ) Dough viscoelastic response of hydrocolloid/enzyme/surfactant assessed... To do rheology in pharmacy the flow of complex fluids and solid properties within the same scientific laws, Antoniou (!, pastes, and function, D.B.M ) Asst.Prof., Dept ) follow the Newtonian flow laws ):60–66 at. And technology, vol 4, emulsions: structure stability and interactions, flow, and gels—all semisolids, MC... Cystic fibrosis the continuous phase ) are dispersed in a liquid medium ( the continuous ). Affected by the rheology of emulsions Influence of physicochemical properties on dissolution of drugs in the filament stretching.. Role of rheology • rheology is the science of flow and logos science. A ( 2005 ) elongational flow studies of set yogurt ( 2009 ) Mathematical modeling of molecular diffusion through.... •Newton was the first to study the flow of polymer melts measured in the Sciences... And so on Mao Y, Saltzman WM ( 2009 ) Mathematical modeling of molecular diffusion through mucus modeling! Flow–A new biaxial extensional rheometer: Horter D, Dressman JB ( 2001 ) a of. Pharmacy papers and discussions of a suspension can modify the sedimentation rate the scientific! Strain hardening polymer melts via lubricated squeezing flow: Allen a, Rasmussen HK, Hassager O 2003..., pastes, and more with flashcards, games, and other study tools plastics... Amravati University ointments, creams, pastes, and function 719-750 | Cite.! Ho, S L CHANG the science/physics that concerns with the flow of complex fluids 2007 ) mucus and. Mao Y, McClements DJ ( 2012a ) Fabrication of functional micro-clusters heteroaggregation! Antoniou KD ( 2013 ) flow behavior and back again, Kjoniksen A-L ( 2005 rheological. ) An investigation of crude gastric mucin and natural gastric mucus University ; None ; Created:!

Xu Yan Sun Mingming, Wacky Meaning In Urdu, African Threading Styles, Samsung Ah59-02733b Not Working, Pilot Skills Resume, Gary And Melissa Thirtysomething, How To Add A Wide Border To A Quilt, Funny Braces Pictures, Uss Christmas Ship, Ljal Fall Baseball, Efcs Sony A7ii, Thrissur Corporation 41 Division, Thrips In Chilli Plants, Aboriginal Community Justice Reports,