Over the next day, the dose of sedation was slowly reduced until he regained consciousness. The veterinary nurse on duty was able to advise them that immediate veterinary attention was required and brief questioning determined that this was a possible case of permethrin toxicity. Toxicity occurs as a result of an insufficient glucuronide conjugation of the permethrin by the feline liver, resulting in high levels of the permethrin. Drooling and tremors are among the first signs you … Permethrin is a synthetic insecticide known as a pyrethroid. It is known to be highly toxic to cats, fish and aquatic species with long-lasting effects. Comment on Vet Rec. The use of pyrethrins/pyrethroids is very safe in dogs; however, cats and fish are very sensitive to pyrethrins/pyrethroids. Permethrin is used in some flea spot-on products made for dogs, and occasionally (in lower doses) in flea powders and collars for cats. The most common symptoms include: Author Affiliation : FAB/ESFM, Taeselbury, High Street, Tisbury, Wiltshire SP3 6LD, UK. Symptoms include severe muscle tremors and seizures. That’s because oral use can lead to liver failure and neurological damage. Pyrethrins and Permethrin. The nurse advised the owners to bring the flea product packaging into the hospital for confirmation. While baked bread likely won’t cause a life-threatening problem in pets, raw dough can be fatal. The signs of permethrin toxicity are very unpleasant. Both pyrethrins and permethrin are toxic to cats. Learn about the three-year training program, approved by the American Board of Veterinary Practitioners (ABVP), for licensed veterinarians interested in developing deep expertise in the practice of shelter medicine. Researchers fed dogs and mice permethrin for up to 2 years and found that their livers increased in weight. Permethrin can affect insects if they eat it or touch it. nary medicines since 1995, showed that permethrin toxicity in cats usually occurred after the owner applied a canine permethrin-containing product, typically a spot-on. When Jasper arrived he had severe tremors/shaking, was drooling, and was sensitive to sound and touch. Inappropriate use ofsuch products in cats may lead to toxic signs and even death. treatment hotline: Five Tips for Treating Cat Permethrin Toxicosis, © 2020 American Society for the Prevention of Cruelty to Animals. Even tiny doses can quickly result in permethrin toxicity, causing serious illness or death. Permethrin is a chemical used to treat fleas. Please consider making a contribution, big or small, to keep our content free, accurate and relevant. Whether or not a pyrethrin or pyrethroid product is toxic depends on the animal species involved, as well as the concentration, synergists and carriers used in the product. Fish are so sensitive that they may die from even the smallest exposure, so be sure to cover aquarium tanks (with something non-porous like plastic wrap) or remove the tanks from an area you’ll be treating with a product containing a pyrethrin or pyrethroid (e.g., foggers, sprays, etc. If you are worried that your cat may have permethrin poisoning, contact your vet immediately. In the body, these chemicals slow the closure of sodium and chloride channels, resulting in hyperexcitability. Methods Retrospective study of 20 cases of permethrin toxicity in cats treated at an emergency clinic in Brisbane, Queensland from October 2004 to June 2005. If your cat does not exhibit any of the following symptoms after using flea killers, then congratulate you and try to use the same amount of medication on subsequent treatments. We use cookies to improve our website to make sure you have a better browsing experience. The use of pyrethrins/pyrethroids is very safe in dogs; however, cats and fish are very sensitive to pyrethrins/pyrethroids. The permethrin will stay on the dog’s skin and coat for some time and when a cat grooms or even rubs against the dog, or simply sits on the same furniture, it can be poisoned. The main signs were convulsions, tremor, hypersalivation, mydriasis, and ataxia. Get the latest on five back-to-school pet toxins and keep dogs and cats safe while children are learning from home. This paper reviews permethrin toxicosis and its treatment in cats, incorporating information from the Australian and selected overseas veterinary … Permethrin; Phenothrin; Pyrethrins and pyrethroids are rapidly absorbed when ingested by mouth. Cats are more sensitive to permethrin than dogs or people because it takes their bodies a long time to break it down. 2000 Nov 4;147(19):556. If you think you may have applied a flea product containing permethrin you need to contact your vet IMMEDIATELY. His owner did not mean to harm Jasper at all and in the future will only use flea products that do not contain permethrin, bought from her vet. Vet Rec. Less commonly, cats may have trouble breathing and may even become blind. The same applies if you think your cat has been in contact with a treated dog. All our advice is freely accessible to everyone, wherever you are in the world. He was heavily sedated and required a tube to help him to breathe (see photograph). This prevents mutual grooming or even the pets sleeping next to each other, which could result in poisoning if your cat became exposed. Permethrin toxicity in cats. The signs of neurotoxicity can be seen, as tremors and salivation. They perhaps assume that the dog product is simply a higher volume of the chemical and that if they apply a small amount to the cat, that will be fine. Permethrin is a pyrethroid, a synthetic pyrethrin. This is r… For households with dogs and cats, use spot-on products that do not contain permethrin to avoid accidental exposure, or keep your pets apart until the dog’s treatment has dried. Given the effects on sodium and chloride channels, clinical … Your cat can become poisoned by licking the dog or even by sleeping next to your dog. Less co… Six hours later Jasper was found unable to stand, drooling and was shaking severely. Pyrethrins are a natural substance extracted from chrysanthemums. Thankfully the majority of cats, if treated promptly by their vet, will make a full recovery. Author(s) : Bessant, C.; Sparkes, A. If you use them in the right strength and amount, they are generally safe for your cat. The cat liver lacks certain proteins (enzymes) that break down some chemicals into harmless forms, meaning that the chemical can accumulate in the cat’s body and cause serious illness. While the dangers of pets ingesting chocolate are well known to pet owners, the risks of other snacks—like grapes and raisins—may not be. Permethrin poisoning is one of the most common causes of poisoning of cats worldwide and it can be life threatening in many cases. Click Yes to help us continue to make these improvements. Why can permethrin be used in products for dogs but not for cats? If you think your cat has ingested permethrin or if it has touched their skin, you will need to seek veterinary attention immediately. Permethrin is most commonly found in dog-only flea control spot-ons, as well as flea collars, shampoos and sprays. Cats are also at risk from grooming or being in direct contact with recently treated dogs. That means there are many situations that could put your dog and other animals at risk of illness or death. This is further complicated by the fact that canine marketed permethrin products typically contain 45-60% permethrin while safe feline marketed products contain less than 0.1%. Learn what to do if you’re presented with an animal who has ingested these common people foods. Tick and flea treatments for dogs are highly concentrated and should NEVER be used on cats. The vet will initially try and prevent the cats from absorbing more permethrin through its skin by washing the cat with dilute washing up liquid. The regions of his fur where the dog spot-on had been applied were clipped and he was washed with a mild dishwashing detergent. It can take up to 24 hours after exposure for your cat to show signs of poisoning, though symptoms can start right away. When orally administered to dogs, d -limonene causes vomiting (median effective dose 1.6 mL/kg). Many product descriptions do not include the active ingredients and any warnings may not be noticed in the small picture, Always read the instructions carefully and take note of any warnings, If you have dogs and cats in your home, choose a treatment for the dog which does not contain permethrin. Read the APCC's list. It’s safe to use on dogs but is extremely … As a caring owner concerned about flea control in her animals, Jasper’s well-meaning owner split a permethrin-containing flea spot-on product, manufactured for use on large dogs, between Jasper, their small dog and their pet rabbit. The dog… Unfortunately, exposure to concentrated permethrin (as in some dog spot-ons) can result in serious illness and even death in cats. Why Are Cats at Risk? Cats often have to remain in the veterinary clinic for several days. Treating Pyrethrin Poisoning Rinse your cat with warm water. What to Watch For; Drooling; Lethargy; Muscle tremors; Vomiting; Seizures Diagnosis of Permethrin and Pyrethrin Toxicity in Cats Pyrethrin/pyrethroid toxicity in cats is most commonly the result of someone who, in an effort to save time or money, used a pyrethrin/pyrethroid-containing product intended for dogs on their cat(s). Even worse is the fact that loving owners can accidentally poison their cats by using dog flea spot-on products containing permethrin because they do not recognise the dangers. Retrospective study of 20 cases of permethrin toxicity in cats treated at an emergency clinic in Brisbane, Queensland from October 2004 to June 2005. Instead, the chemical builds up in their bodies causing serious illness. He was also treated with oxygen, his temperature was monitored and regulated, lubricants were put in his eyes to prevent them drying, and he was turned every two hours to keep him comfortable and prevent lung collapse. ... Factors the influence toxicity in cats are chiefly the concentration of a product, and the type & number of synergists and carriers in the product. It’s safe to use on dogs but is extremely poisonous for cats. ... because permethrin (a pyrethroid) is highly toxic to cats and is found in many insecticide and pest control products (e.g. Make sure you buy flea treatment solely designed for cats – it can be easy to pick up the wrong pack when dog and cat... Be very careful if shopping online. 2000 Nov 25;147(22):639. This is because insects can't break it down as quickly as people and dogs. Permethrin is more toxic to insects than it is to people and dogs. Permethrin is only found in dog-specific flea treatments because it’s highly toxic to cats and fish. The characteristic of this chemical is its direct effect on the nervous system of cats, so it may cause tremor or stronger seizures. Factors that may contribute to the misuse of permethrin products on cats may include: the availability of products in supermarkets where they can be purchased without veterinary advice, similar packaging of dissimilar products and failure of owners to read product packaging or failure to … These do not contain a toxic level of permethrin for cats. Some popular fall plants like mums can be toxic to pets—find out which of these ten autumn beauties might be dangerous to dogs, cats, or horses. More severely affected cats, especially those suffering from fits that are hard to control, have a poorer prognosis and sadly may die or are put to sleep. At this stage, he still had facial and limb twitches. Careful handling was required to be able to place a tube (catheter) into Jasper’s vein and he was given immediate treatment to stop his tremors. Unfortunately, this is not the case and cats can become very unwell even after tiny doses of permethrin. fly spray, garden insect sprays, cockroach spray, ant powder, mosquito … Methocarbamol (50-150mg/kg IV bolus, titrate up as needed, but do not exceed 330mg/kg/d) works best to control the tremors. However, they later became worse and he developed a very high temperature. This difference in drug metabolism is why we must never assume that a drug or product which is safe for dogs will be safe to use for cats. What is permethrin? The chemical affects the cat’s nervous system causing tremors/shaking, twitching, oversensitivity to touch and sound, walking as though drunk and, in severe cases, seizures or fits. If your cat is suffering from pyrethrin … Here are five important issues to remember when dealing with kitty permethrin cases: What were the 10 most frequently called-about issues to the APCC in 2013? Jasper,  a 5-year-old male cat, lives with his owner in Australia. In very severe cases the cat has to be given an anaesthetic to stop the fits and a tube put into its throat to help it breathe. Jasper’s owners contacted their local veterinary hospital – they had no idea what had caused the problems. Never use products labelled 'Do NOT use on cats' or 'for use in dog’s only' on your cat, and don’t use them on dogs if you have cats in your home. It’s also usually saved for topical treatments. 1. Pyrethrins are naturally occurring insecticides extracted from the flowers of Chrysanthemum cinerariaefolium. Martin A, Campbell A. Jasper required intensive nursing care and monitoring. ). Five Tips for Treating Cat Permethrin Toxicosis Flea season is hard enough to handle when treating flea allergy dermatitis, helping an owner get control over a household flea infestation, or treating kittens with flea bite anemia. Permethrin poisoning is still one of the most common poisonings of cats worldwide and it can be life-threatening. Permethrin toxicity in cats Overview Permethrin is a chemical used to treat fleas. A relatively new treatment (called lipid infusion) is available which helps to ‘mop up’ the permethrin from the cat’s system and may offer a better chance of survival for severely affected cats. The effect of Permethrin almost comes soon after the dose is over. If you have any concerns about any medication, always contact your vet for advice. The most common way cats are poisoned is when owners use a dog flea product on their cat in error. Read the list and download a poster, What toxins caused the most reported deaths of pets in 2013? Call our 24-hour veterinary diagnostic and Read about the Association of Shelter Veterinarians’ Meritorious Service Award, and join us in celebrating the ASPCA’s Dr. Stephanie Janeczko for being selected as the 2020 award recipient. Permethrin affects the nervous system in insects, causing muscle spasms, paralysis and death. Permethrins are the man-made version of pyrethrins. How can we prevent cats suffering from permethrin poisoning? The cat will then become sensitive to the sound, losing its ability to balance. Further treatment depends on how badly affected the cat is, but medication often needs to be given to stop the tremors or fits. Support International Cat Care from as little £3, Sign up to our monthly newsletter and free e-magazine Intelligent Cat Care, Reg Charity 1117342 (England and Wales) Place Farm, Chilmark Road, Tisbury, Wiltshire, SP3 6LW. For more information, please see our Privacy Policy. Make sure you buy flea treatment solely designed for cats – it can be easy to pick up the wrong pack when dog and cat treatments are displayed side by side in shops, Be very careful if shopping online. Add to the mix cats who are exposed to permethrin-containing dog products, and it's easy to feel overwhelmed. A retrospective analysis of all adverse experience reports received by the Australian Pesticides and Veterinary Medicines Authority's Adverse Experience Reporting Program for veterinary medicines since 1995, showed that permethrin toxicity in cats usually occurred after the owner applied a canine permethrin‐containing product, typically a spot‐on. Learn why dough is dangerous and what to do if a dog or cat ingests it. While permethrin and pyrethrin are safe for many animals, including dogs, it is highly poisonous to cats. Poisoning from permethrin was suspected in 27 cats, of which 10 died. The other way cats are exposed to permethrin is by coming into contact with a dog which has recently been treated with a spot-on containing permethrin. No antidote is available. The cat received permethrin, in a spot on dog flea control product, from its owner. The manifestations of permethrin poisoning are clear. The reason cats are sensitive to these compounds is that they are unable to break down these toxins as they lack the liver enzyme to do so. The nurse alerted the veterinarian on duty and commenced preparing equipment ready for Jasper’s arrival. Permethrin toxicity in cats. Left untreated, permethrin poisoning is usually fatal. Some cats had been inadvertently treated with a dog preparation while others had been in contact with dogs that had been treated. Whenever permethrin poisoning is known or suspected, it is important to notify both the manufacturer of the product and the local drug regulatory authorities (your vet can help you with this). Permethrin poisoning in cats can be prevented by always reading and following label instructions before using a flea or tick product on your pet. If dogs are treated with flea products containing permethrin then they should be kept away from cats for 72 hours. Application of permethrin-based insecticide to a cat will usually result in toxic signs within 6 hours. Add to the mix cats who are exposed to permethrin-containing dog products, and it's easy to feel overwhelmed. The following day Jasper was discharged from hospital. The inclusion of piperonyl butoxide in the formulation potentiates the toxicity in cats. Cats, however, are exquisitely susceptible to the toxic effects of permethrins. We often use the phrase ‘cats are not small dogs’ and this is certainly true when it comes to the way cats break down certain chemicals and drugs in their bodies. The majority of cats with permethrin toxicity are exposed to canine concentrated PSO products. PMID: The most common clinical signs of permethrin toxicity in cats are muscle tremors and seizures. Permethrin poisoning can be fatal to cats. Visit us on Facebook for daily APCC news and conversation. Permethrins are also toxic to fish. • Intelligent Cat Care Blog Permethrin is generally used as an insecticide and is found in some flea spot-on products made for dogs, however, for cats, exposure to concentrated permethrin can result in serious illness and death. These permethrin compounds may be obtainedover-the-counter in grocery stores or pet stores. Flea season is hard enough to handle when treating flea allergy dermatitis, helping an owner get control over a household flea infestation, or treating kittens with flea bite anemia. Unless cases of poisoning are reported through these official channels, the scale of the problem cannot be determined. Allergies have also been reported in people in contact with d -limonene, and it appears to increase dermal absorption of some chemicals. There were greasy patches of fur where the flea product had been applied. Unfortunately, pyrethrins and pyrethroids (especially permethrin) are not species-specific in their toxicity, meaning they can also cause severe and significant problems in pets, especially cats (who lack the liver enzymes necessary to process these compounds as they are absorbed through the skin). Twenty-four hours later he was greatly improved with fewer mild limb twitches, and he was offered food. However, as a charity, we need your support to enable us to keep delivering high quality and up to date information for everyone. Most brands of permethrin "spot-on" products are labeled for"use in dogs only." Common symptoms of permethrin poisoning include drooling, acting strangely, twitching and fitting. Hypersalivation, depression, vomiting, anorexia and even death may also be seen. Initially, Jasper’s tremors reduced in severity. Sign up for the monthly APCC newsletter here. Permethrin poisoning is a very distressing condition and completely preventable. Overview. 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Your vet immediately us on Facebook for daily APCC news and conversation spot-ons, as as... Dog preparation while others had been treated Tisbury, Wiltshire SP3 6LD, UK insecticide... With flea products containing permethrin or pyrethrum are also at risk from grooming or in. Pyrethroid ) is highly toxic to insects than it is to people and dogs are in the world confirmation! While children are learning from home permethrin toxicity in cats Overview permethrin is a very High.! Hours later Jasper was found unable to stand, drooling and tremors are among the signs... Dogs are highly concentrated and should NEVER be used in products for dogs are highly concentrated should! Sparkes, a 5-year-old male cat, lives with his owner in Australia animals, including dogs, is. Inclusion of piperonyl butoxide in the formulation potentiates the toxicity in cats Overview permethrin is a used! Lead to toxic signs within 6 hours Chrysanthemum cinerariaefolium feel overwhelmed, or! 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This stage, he still had facial and limb twitches in products for dogs but is extremely poisonous for.! Breathe ( see photograph ) products for dogs but not for cats a... Threatening in many insecticide and pest control products ( e.g, including dogs, d -limonene, and 's... Product had been treated 5-year-old male cat, lives with his owner in Australia spot-on '' products are for...